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Exosomal cell-to-cell transmission of alpha synuclein oligomers
BACKGROUND: Aggregation of alpha-synuclein (αsyn) and resulting cytotoxicity is a hallmark of sporadic and familial Parkinson’s disease (PD) as well as dementia with Lewy bodies, with recent evidence implicating oligomeric and pre-fibrillar forms of αsyn as the pathogenic species. Recent in vitro st...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3483256/ https://ncbi.nlm.nih.gov/pubmed/22920859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-7-42 |
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