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Pharmacogenetic considerations with dichloroacetate dosing
The investigational drug dichloroacetate (DCA) is a metabolic regulator that has been successfully used to treat acquired and congenital metabolic diseases and, recently, solid tumors. Its clinical use has revealed challenges in selecting appropriate doses. Chronic administration of DCA leads to inh...
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| Veröffentlicht in: | Pharmacogenomics |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Future Medicine Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5558523/ https://ncbi.nlm.nih.gov/pubmed/27143230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2015-0012 |
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