Joint inflammation related citrullination of functional arginines in extracellular proteins

We report the extent, specific sites and structural requirements of joint inflammation related citrullination in extracellular proteins. A total of 40 synovial fluid samples derived from chronically inflamed human joints were analysed by heparin-agarose fractionation and LC-MS/MS. Citrullination of...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Sipilä, Kalle H., Ranga, Vipin, Rappu, Pekka, Mali, Markku, Pirilä, Laura, Heino, Ilona, Jokinen, Johanna, Käpylä, Jarmo, Johnson, Mark S., Heino, Jyrki
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557964/
https://ncbi.nlm.nih.gov/pubmed/28811641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08597-4
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