Frontline Science: Eosinophil-deficient MBP-1 and EPX double-knockout mice link pulmonary remodeling and airway dysfunction with type 2 inflammation

Eosinophils and the release of cationic granule proteins have long been implicated in the development of the type 2–induced pathologies linked with respiratory inflammation. Paradoxically, the ablation of the two genes encoding the most abundant of these granule proteins, major basic protein-1 (MBP-...

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Bibliografski detalji
Izdano u:J Leukoc Biol
Glavni autori: Ochkur, Sergei I., Doyle, Alfred D., Jacobsen, Elizabeth A., LeSuer, William E., Li, Wen, Protheroe, Cheryl A., Zellner, Katie R., Colbert, Dana, Shen, HuaHao H., Irvin, Charlie G., Lee, James J., Lee, Nancy A.
Format: Artigo
Jezik:Inglês
Izdano: Society for Leukocyte Biology 2017
Teme:
Spotlight on Leading Edge Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557640/
https://ncbi.nlm.nih.gov/pubmed/28515227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI1116-488RR
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