HIF is not essential for suppression of experimental tumor growth by mTOR inhibition

The Hypoxia Inducible Transcription Factor (HIF) is the master regulator of cellular response to hypoxic adaptation. Solid tumors inevitably harbour hypoxic regions with subsequent stabilization and activation of HIF and HIF target genes due to poor vascularization and rapid growth. The mammalian ta...

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Detaylı Bibliyografya
Yayımlandı:J Cancer
Asıl Yazarlar: Knaup, Karl X., Guenther, Regina, Stoeckert, Johanna, Monti, Juliana M., Eckardt, Kai-Uwe, Wiesener, Michael S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556644/
https://ncbi.nlm.nih.gov/pubmed/28819378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.16486
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