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CHONDROCYTE AUTOPHAGY IS STIMULATED BY HIF-1 DEPENDENT AMPK ACTIVATION AND mTOR SUPPRESSION
The goal of the study is to examine the relationship between the sensor molecules, Hypoxia Inducible Factor-1 (HIF-1), AMP activated Protein Kinase (AMPK) and mammalian Target of Rapamycin (mTOR) in chondrocyte survival and autophagy. We showed that chondrocytes expressed the energy sensor AMPK-1 an...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2828515/ https://ncbi.nlm.nih.gov/pubmed/19830459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-009-1310-y |
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