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Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

The overall goal of the investigation was to examine autophagy in the growth plate and to ascertain how this process was regulated. Herein, we show that in the postmitotic maturing zone of the growth plate, chondrocytes express an autophagic phenotype. This robust and particulate immunohistochemical...

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Autors principals: Srinivas, Vickram, Bohensky, Jolene, Shapiro, Irving M.
Format: Artigo
Idioma:Inglês
Publicat: S. Karger AG 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677069/
https://ncbi.nlm.nih.gov/pubmed/18703865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151428
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