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Autophagy: A New Phase in the Maturation of Growth Plate Chondrocytes Is Regulated by HIF, mTOR and AMP Kinase

The overall goal of the investigation was to examine autophagy in the growth plate and to ascertain how this process was regulated. Herein, we show that in the postmitotic maturing zone of the growth plate, chondrocytes express an autophagic phenotype. This robust and particulate immunohistochemical...

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Detalhes bibliográficos
Main Authors: Srinivas, Vickram, Bohensky, Jolene, Shapiro, Irving M.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677069/
https://ncbi.nlm.nih.gov/pubmed/18703865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000151428
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