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Oxygen Tension Regulates the Expression of ANK (Progressive Ankylosis) in an HIF-1–Dependent Manner in Growth Plate Chondrocytes

The proximal promoter region of ANK, a gene that codes for a protein that regulates the transport of inorganic pyrophosphate, contains two hypoxia responsive elements (HREs); therefore, we studied the expression and function of ANK at different oxygen tensions. ATDC5 and N1511 clonal chondrocytic ce...

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Detalhes bibliográficos
Main Authors: Zaka, Raihana, Dion, Arnold S., Kusnierz, Anna, Bohensky, Jolene, Srinivas, Vickram, Freeman, Theresa, Williams, Charlene J.
Formato: Artigo
Idioma:Inglês
Publicado em: Amer Soc Bone & Mineral Res. 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765931/
https://ncbi.nlm.nih.gov/pubmed/19419319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.090512
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