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HYPOXIC INDUCTION OF UCP3 IN THE GROWTH PLATE: UCP3 SUPPRESSES CHONDROCYTE AUTOPHAGY

The overall goal of the investigation was to examine the role of uncoupling proteins (UCP’s) in regulating late stage events in the chondrocyte maturation pathway. We showed for the first time that epiphyseal chondrocytes expressed UCP3. In hypoxia, UCP3 mediated regulation of the mitochondrial tran...

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Detalhes bibliográficos
Main Authors: Watanabe, Hitoshi, Bohensky, Jolene, Freeman, Theresa, Srinivas, Vickram, Shapiro, Irving M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679164/
https://ncbi.nlm.nih.gov/pubmed/18288636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21408
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