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HYPOXIC INDUCTION OF UCP3 IN THE GROWTH PLATE: UCP3 SUPPRESSES CHONDROCYTE AUTOPHAGY

The overall goal of the investigation was to examine the role of uncoupling proteins (UCP’s) in regulating late stage events in the chondrocyte maturation pathway. We showed for the first time that epiphyseal chondrocytes expressed UCP3. In hypoxia, UCP3 mediated regulation of the mitochondrial tran...

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Autori principali: Watanabe, Hitoshi, Bohensky, Jolene, Freeman, Theresa, Srinivas, Vickram, Shapiro, Irving M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2679164/
https://ncbi.nlm.nih.gov/pubmed/18288636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21408
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