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EEA1 restores homeostatic synaptic plasticity in hippocampal neurons from Rett syndrome mice

KEY POINTS: Rett syndrome is a neurodevelopmental disorder caused by loss‐of‐function mutations in MECP2, the gene encoding the transcriptional regulator methyl‐CpG‐binding protein 2 (MeCP2). Mecp2 deletion in mice results in an imbalance of excitation and inhibition in hippocampal neurons, which af...

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Bibliografske podrobnosti
izdano v:J Physiol
Main Authors: Xu, Xin, Pozzo‐Miller, Lucas
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5556154/
https://ncbi.nlm.nih.gov/pubmed/28621434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274450
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