The BDNF val-66-met Polymorphism Affects Neuronal Morphology and Synaptic Transmission in Cultured Hippocampal Neurons from Rett Syndrome Mice

Brain-derived neurotrophic factor (Bdnf) has been implicated in several neurological disorders including Rett syndrome (RTT), an X-linked neurodevelopmental disorder caused by loss-of-function mutations in the transcriptional modulator methyl-CpG-binding protein 2 (MECP2). The human BDNF gene has a...

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Опубликовано в: :Front Cell Neurosci
Главные авторы: Xu, Xin, Garcia, Jordi, Ewalt, Rachel, Nason, Shelly, Pozzo-Miller, Lucas
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017
Предметы:
Neuroscience
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508027/
https://ncbi.nlm.nih.gov/pubmed/28751857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00203
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