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EEA1 restores homeostatic synaptic plasticity in hippocampal neurons from Rett syndrome mice
KEY POINTS: Rett syndrome is a neurodevelopmental disorder caused by loss‐of‐function mutations in MECP2, the gene encoding the transcriptional regulator methyl‐CpG‐binding protein 2 (MeCP2). Mecp2 deletion in mice results in an imbalance of excitation and inhibition in hippocampal neurons, which af...
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| Publié dans: | J Physiol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
John Wiley and Sons Inc.
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5556154/ https://ncbi.nlm.nih.gov/pubmed/28621434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274450 |
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