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Secondary structure in the target as a confounding factor in synthetic oligomer microarray design
BACKGROUND: Secondary structure in the target is a property not usually considered in software applications for design of optimal custom oligonucleotide probes. It is frequently assumed that eliminating self-complementarity, or screening for secondary structure in the probe, is sufficient to avoid i...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2005
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC555549/ https://ncbi.nlm.nih.gov/pubmed/15755320 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-6-31 |
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