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Application of Equilibrium Models of Solution Hybridization to Microarray Design and Analysis

BACKGROUND: The probe percent bound value, calculated using multi-state equilibrium models of solution hybridization, is shown to be useful in understanding the hybridization behavior of microarray probes having 50 nucleotides, with and without mismatches. These longer oligonucleotides are in widesp...

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Bibliografske podrobnosti
Main Authors: Gharaibeh, Raad Z., Newton, Joshua M., Weller, Jennifer W., Gibas, Cynthia J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883574/
https://ncbi.nlm.nih.gov/pubmed/20548788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011048
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