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The impact of RNA secondary structure on read start locations on the Illumina sequencing platform
High-throughput sequencing is subject to sequence dependent bias, which must be accounted for if researchers are to make precise measurements and draw accurate conclusions from their data. A widely studied source of bias in sequencing is the GC content bias, in which levels of GC content in a genomi...
Zapisane w:
Wydane w: | PLoS One |
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Główni autorzy: | , , |
Format: | Artigo |
Język: | Inglês |
Wydane: |
Public Library of Science
2017
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Hasła przedmiotowe: | |
Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5330537/ https://ncbi.nlm.nih.gov/pubmed/28245230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173023 |
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