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The impact of RNA secondary structure on read start locations on the Illumina sequencing platform

High-throughput sequencing is subject to sequence dependent bias, which must be accounted for if researchers are to make precise measurements and draw accurate conclusions from their data. A widely studied source of bias in sequencing is the GC content bias, in which levels of GC content in a genomi...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Price, Adam, Garhyan, Jaishree, Gibas, Cynthia
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2017
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5330537/
https://ncbi.nlm.nih.gov/pubmed/28245230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173023
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