A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression

Activation-induced cytidine deaminase (AID) is essential for somatic hypermutations (SHM) and class switch recombination. Overexpression of AID in non-B cells can induce SHM in artificial constructs inserted in various loci in the genome. AID overexpression was thus proposed to introduce mutations i...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Kotani, Ai, Okazaki, Il-mi, Muramatsu, Masamichi, Kinoshita, Kazuo, Begum, Nasim A., Nakajima, Toshiharu, Saito, Hirohisa, Honjo, Tasuku
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2005
נושאים:
Biological Sciences
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC555529/
https://ncbi.nlm.nih.gov/pubmed/15767564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0500830102
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים