Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle

Bacteria stimulate macrophages as part of normal host defense. However, when this response is not limited, vascular smooth muscle may also be activated to express “vasoactive” genes (e.g., cyclooxygenase), leading to vascular collapse and septic shock. In macrophages, Toll-like receptors (TLRs) 4 an...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jimenez, Rosario, Belcher, Elizabeth, Sriskandan, Shiranee, Lucas, Ruth, McMaster, Shaun, Vojnovic, Ivana, Warner, Timothy D., Mitchell, Jane A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2005
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC555494/
https://ncbi.nlm.nih.gov/pubmed/15755814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407655101
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