Role of Toll-like receptors 2 and 4 in the induction of cyclooxygenase-2 in vascular smooth muscle

Bacteria stimulate macrophages as part of normal host defense. However, when this response is not limited, vascular smooth muscle may also be activated to express “vasoactive” genes (e.g., cyclooxygenase), leading to vascular collapse and septic shock. In macrophages, Toll-like receptors (TLRs) 4 an...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Jimenez, Rosario, Belcher, Elizabeth, Sriskandan, Shiranee, Lucas, Ruth, McMaster, Shaun, Vojnovic, Ivana, Warner, Timothy D., Mitchell, Jane A.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2005
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC555494/
https://ncbi.nlm.nih.gov/pubmed/15755814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0407655101
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