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β-Amyloid Prions and the Pathobiology of Alzheimer’s Disease

Alzheimer’s disease (AD) is the most common neurodegenerative disease in humans and will pose a considerable challenge to healthcare systems in the coming years. Aggregation of the β-amyloid (Aβ) peptide within the brain is thought to be an initiating event in AD pathogenesis. Many recent studies in...

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Publicat a:Cold Spring Harb Perspect Med
Autors principals: Watts, Joel C., Prusiner, Stanley B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554751/
https://ncbi.nlm.nih.gov/pubmed/28193770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a023507
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