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Cancer progression by reprogrammed BCAA metabolism in myeloid leukemia
Reprogrammed cellular metabolism is a common characteristic observed in various cancers(1,2). However, whether metabolic changes directly regulate cancer development and progression remains poorly understood. Here we show that BCAT1, a cytosolic aminotransferase for the branched-chain amino acids (B...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554449/ https://ncbi.nlm.nih.gov/pubmed/28514443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature22314 |
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