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Classifying kinase conformations using a machine learning approach
BACKGROUND: Signaling proteins such as protein kinases adopt a diverse array of conformations to respond to regulatory signals in signaling pathways. Perhaps the most fundamental conformational change of a kinase is the transition between active and inactive states, and defining the conformational f...
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| Опубликовано в: : | BMC Bioinformatics |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290640/ https://ncbi.nlm.nih.gov/pubmed/28152981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1506-2 |
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