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RNA binding protein MSI2 positively regulates FLT3 expression in myeloid leukemia

FLT3 is frequently mutated and overexpressed in acute myelogenous leukemia (AML) and other hematologic malignancies. Although signaling events downstream of FLT3 receptor tyrosine kinase have been studied in depth, molecular mechanisms of how FLT3 expression is regulated at the post-transcriptional...

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Detalhes bibliográficos
Publicado no:Leuk Res
Main Authors: Hattori, Ayuna, McSkimming, Daniel, Kannan, Natarajan, Ito, Takahiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5508866/
https://ncbi.nlm.nih.gov/pubmed/28107692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2017.01.015
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