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Nuclear phosphorylated Dicer processes double-stranded RNA in response to DNA damage
The endoribonuclease Dicer is a key component of the human RNA interference pathway and is known for its role in cytoplasmic microRNA production. Recent findings suggest that noncanonical Dicer generates small noncoding RNA to mediate the DNA damage response (DDR). Here, we show that human Dicer is...
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| Publicat a: | J Cell Biol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5551710/ https://ncbi.nlm.nih.gov/pubmed/28642363 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201612131 |
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