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The cohesin complex prevents Myc-induced replication stress

The cohesin complex is mutated in cancer and in a number of rare syndromes collectively known as Cohesinopathies. In the latter case, cohesin deficiencies have been linked to transcriptional alterations affecting Myc and its target genes. Here, we set out to understand to what extent the role of coh...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Rohban, Sara, Cerutti, Aurora, Morelli, Marco J, d'Adda di Fagagna, Fabrizio, Campaner, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550886/
https://ncbi.nlm.nih.gov/pubmed/28749464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.345
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