Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis

In eukaryotes, the initiation of DNA replication involves the ordered assembly on chromatin of pre-replicative complexes (pre-RCs), including the origin recognition complex (ORC), Cdc6, Cdt1 and the minichromosome maintenance proteins (MCMs). In light of its indispensable role in the formation of pr...

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Detalles Bibliográficos
Main Authors: Pelizon, Cristina, d’Adda di Fagagna, Fabrizio, Farrace, Lorena, Laskey, Ronald A.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2002
Assuntos:
Scientific Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084215/
https://ncbi.nlm.nih.gov/pubmed/12151338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf161
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