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Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1
In yeasts, the replication protein Cdc6/Cdc18 is required for the initiation of DNA replication and also for coupling S phase with the following mitosis. In metazoans a role for Cdc6 has only been shown in S phase entry. Here we provide evidence that human Cdc6 (HuCdc6) also regulates the onset of m...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC140731/ https://ncbi.nlm.nih.gov/pubmed/12554670 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg046 |
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