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Regulation of the replication initiator protein p65(cdc18) by CDK phosphorylation

Cyclin-dependent kinases (CDKs) promote the initiation of DNA replication and prevent reinitiation before mitosis, presumably through phosphorylation of key substrates at origins of replication. In fission yeast, the p65(cdc18) protein is required to initiate DNA replication and interacts with the o...

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Autors principals: Jallepalli, Prasad V., Brown, Grant W., Muzi-Falconi, Marco, Tien, Deborah, Kelly, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316667/
https://ncbi.nlm.nih.gov/pubmed/9353247
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