Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1
In yeasts, the replication protein Cdc6/Cdc18 is required for the initiation of DNA replication and also for coupling S phase with the following mitosis. In metazoans a role for Cdc6 has only been shown in S phase entry. Here we provide evidence that human Cdc6 (HuCdc6) also regulates the onset of m...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2003
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC140731/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12554670/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdg046 |
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