The cohesin complex prevents Myc-induced replication stress

The cohesin complex is mutated in cancer and in a number of rare syndromes collectively known as Cohesinopathies. In the latter case, cohesin deficiencies have been linked to transcriptional alterations affecting Myc and its target genes. Here, we set out to understand to what extent the role of coh...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Rohban, Sara, Cerutti, Aurora, Morelli, Marco J, d'Adda di Fagagna, Fabrizio, Campaner, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550886/
https://ncbi.nlm.nih.gov/pubmed/28749464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.345
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