ALKBH7 drives a tissue and sex-specific necrotic cell death response following alkylation-induced damage

Regulated necrosis has emerged as a major cell death mechanism in response to different forms of physiological and pharmacological stress. The AlkB homolog 7 (ALKBH7) protein is required for regulated cellular necrosis in response to chemotherapeutic alkylating agents but its role within a whole org...

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Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Jordan, Jennifer J, Chhim, Sophea, Margulies, Carrie M, Allocca, Mariacarmela, Bronson, Roderick T, Klungland, Arne, Samson, Leona D, Fu, Dragony
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550884/
https://ncbi.nlm.nih.gov/pubmed/28726787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.343
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