The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain

Inflammatory responses play a key role in many neural pathologies, with localized signaling from the non-immune cells making critical contributions. The NLRP3 inflammasome is an important component of innate immune signaling and can link neural insult to chronic inflammation. The NLRP3 inflammasome...

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Vydáno v:Front Cell Neurosci
Hlavní autoři: Albalawi, Farraj, Lu, Wennan, Beckel, Jonathan M., Lim, Jason C., McCaughey, Stuart A., Mitchell, Claire H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Neuroscience
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550720/
https://ncbi.nlm.nih.gov/pubmed/28848393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2017.00227
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