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The essential transcriptional function of BRD4 in acute myeloid leukemia cells

Acute myeloid leukemia (AML) is often initiated by genetic alterations of machineries that regulate chromatin and transcription, thereby blocking cell differentiation. Such mechanisms can also render leukemia cells vulnerable to perturbations of transcriptional regulators, which includes small-molec...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Symp Quant Biol
Main Authors: Roe, Jae-Seok, Vakoc, Christopher R.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550326/
https://ncbi.nlm.nih.gov/pubmed/28174254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2016.81.031039
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