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The essential transcriptional function of BRD4 in acute myeloid leukemia cells

Acute myeloid leukemia (AML) is often initiated by genetic alterations of machineries that regulate chromatin and transcription, thereby blocking cell differentiation. Such mechanisms can also render leukemia cells vulnerable to perturbations of transcriptional regulators, which includes small-molec...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cold Spring Harb Symp Quant Biol
Main Authors: Roe, Jae-Seok, Vakoc, Christopher R.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550326/
https://ncbi.nlm.nih.gov/pubmed/28174254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2016.81.031039
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