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The essential transcriptional function of BRD4 in acute myeloid leukemia cells

Acute myeloid leukemia (AML) is often initiated by genetic alterations of machineries that regulate chromatin and transcription, thereby blocking cell differentiation. Such mechanisms can also render leukemia cells vulnerable to perturbations of transcriptional regulators, which includes small-molec...

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Podrobná bibliografie
Vydáno v:Cold Spring Harb Symp Quant Biol
Hlavní autoři: Roe, Jae-Seok, Vakoc, Christopher R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550326/
https://ncbi.nlm.nih.gov/pubmed/28174254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2016.81.031039
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