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The essential transcriptional function of BRD4 in acute myeloid leukemia cells

Acute myeloid leukemia (AML) is often initiated by genetic alterations of machineries that regulate chromatin and transcription, thereby blocking cell differentiation. Such mechanisms can also render leukemia cells vulnerable to perturbations of transcriptional regulators, which includes small-molec...

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Detalhes bibliográficos
Publicado no:Cold Spring Harb Symp Quant Biol
Main Authors: Roe, Jae-Seok, Vakoc, Christopher R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550326/
https://ncbi.nlm.nih.gov/pubmed/28174254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2016.81.031039
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