A Versatile Approach to Site-specifically Install Lysine Acylations in Proteins

Using amber suppression in coordination with a mutant pyrrolysyl-tRNA synthetase-tRNA(Pyl) pair, azidonorleucine is genetically encoded in E. coli. Its genetic incorporation followed by traceless Staudinger ligation with a phosphinothioester allows convenient synthesis of a protein with a site-speci...

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Detaylı Bibliyografya
Yayımlandı:Angew Chem Int Ed Engl
Asıl Yazarlar: Wang, Zhipeng A., Kurra, Yadagiri, Wang, Xin, Zeng, Yu, Lee, Yan-Jiun, Sharma, Vangmayee, Lin, Hening, Dai, Susie Y., Liu, Wenshe R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550319/
https://ncbi.nlm.nih.gov/pubmed/28042700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201611415
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