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Phospha-Michael Addition as a New Click Reaction for Protein Functionalization

A new type of click reaction between alkyl phosphine and acrylamide was developed and applied for site-specific protein labeling in vitro and on live cells. Acrylamide is a small electrophilic olefin that readily undergoes phospha-Michael addition with alkyl phosphine. Our kinetic study indicated a...

詳細記述

保存先:
書誌詳細
出版年:Chembiochem
主要な著者: Lee, Yan-Jiun, Kurra, Yadagiri, Liu, Wenshe R.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5059841/
https://ncbi.nlm.nih.gov/pubmed/26756316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201500697
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