Structural Rearrangement upon Fragmentation of the Stability Core of the ALS-Linked Protein TDP-43

Amyotrophic lateral sclerosis (ALS) is the most common adult degenerative motor neuron disease. Experimental evidence indicates a direct role of transactive-response DNA-binding protein 43 (TDP-43) in the pathology of ALS and other neurodegenerative diseases. TDP-43 has been identified as a major co...

Full description

Saved in:
Bibliographic Details
Published in:Biophys J
Main Authors: Morgan, Brittany R., Zitzewitz, Jill A., Massi, Francesca
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2017
Subjects:
Proteins
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550305/
https://ncbi.nlm.nih.gov/pubmed/28793209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.049
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items