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Structural Rearrangement upon Fragmentation of the Stability Core of the ALS-Linked Protein TDP-43

Amyotrophic lateral sclerosis (ALS) is the most common adult degenerative motor neuron disease. Experimental evidence indicates a direct role of transactive-response DNA-binding protein 43 (TDP-43) in the pathology of ALS and other neurodegenerative diseases. TDP-43 has been identified as a major co...

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Bibliografische gegevens
Gepubliceerd in:Biophys J
Hoofdauteurs: Morgan, Brittany R., Zitzewitz, Jill A., Massi, Francesca
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Biophysical Society 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5550305/
https://ncbi.nlm.nih.gov/pubmed/28793209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.049
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