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Structural Rearrangement upon Fragmentation of the Stability Core of the ALS-Linked Protein TDP-43
Amyotrophic lateral sclerosis (ALS) is the most common adult degenerative motor neuron disease. Experimental evidence indicates a direct role of transactive-response DNA-binding protein 43 (TDP-43) in the pathology of ALS and other neurodegenerative diseases. TDP-43 has been identified as a major co...
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| Publicado no: | Biophys J |
|---|---|
| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5550305/ https://ncbi.nlm.nih.gov/pubmed/28793209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.049 |
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