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Characterization of TDP-43 RRM2 Partially Folded States and Their Significance to ALS Pathogenesis
The human protein TDP-43 is a major component of the cellular aggregates found in amyotrophic lateral sclerosis and other neurodegenerative diseases. Insoluble cytoplasmic aggregates isolated from the brain of amyotrophic lateral sclerosis and frontotemporal lobar degeneration patients contain ubiqu...
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| Udgivet i: | Biophys J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6224623/ https://ncbi.nlm.nih.gov/pubmed/30309612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2018.09.011 |
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