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The Pathobiology of TDP-43 C-Terminal Fragments in ALS and FTLD
During neurodegenerative disease, the multifunctional RNA-binding protein TDP-43 undergoes a vast array of post-translational modifications, including phosphorylation, acetylation, and cleavage. Many of these alterations may directly contribute to the pathogenesis of TDP-43 proteinopathies, which in...
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| Publicado no: | Front Neurosci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6470282/ https://ncbi.nlm.nih.gov/pubmed/31031584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00335 |
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