Transgene Expression in Dogs After Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons Using Balloon Catheters

The Sleeping Beauty transposon system has been extensively tested for integration of reporter and therapeutic genes in vitro and in vivo in mice. Dogs were used as a large animal model for human therapy and minimally invasive infusion of DNA solutions. DNA solutions were delivered into the entire li...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Hum Gene Ther
Prif Awduron: Hyland, Kendra A., Aronovich, Elena L., Olson, Erik R., Bell, Jason B., Rusten, Myra Urness, Gunther, Roland, Hunter, David W., Hackett, Perry B., McIvor, R. Scott
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Mary Ann Liebert, Inc. 2017
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549801/
https://ncbi.nlm.nih.gov/pubmed/28447859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.003
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