Transgene Expression in Dogs After Liver-Directed Hydrodynamic Delivery of Sleeping Beauty Transposons Using Balloon Catheters

The Sleeping Beauty transposon system has been extensively tested for integration of reporter and therapeutic genes in vitro and in vivo in mice. Dogs were used as a large animal model for human therapy and minimally invasive infusion of DNA solutions. DNA solutions were delivered into the entire li...

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Gepubliceerd in:Hum Gene Ther
Hoofdauteurs: Hyland, Kendra A., Aronovich, Elena L., Olson, Erik R., Bell, Jason B., Rusten, Myra Urness, Gunther, Roland, Hunter, David W., Hackett, Perry B., McIvor, R. Scott
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2017
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549801/
https://ncbi.nlm.nih.gov/pubmed/28447859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2017.003
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