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The carboxy-terminal region of the TBC1D4 (AS160) RabGAP mediates protein homodimerization

TBC1D4 (also known as AS160) is a Rab·GTPase-activating protein (RabGAP) which functions in insulin signaling. TBC1D4 is critical for translocation of glucose transporter 4 (GLUT4), from an inactive, intracellular, vesicle-bound site to the plasma membrane, where it promotes glucose entry into cells...

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Detalles Bibliográficos
Publicado en:Int J Biol Macromol
Autores principales: Woo, Ju Rang, Kim, Soon-Jong, Kim, Keon Young, Jang, Hyonchol, Shoelson, Steven E., Park, SangYoun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548637/
https://ncbi.nlm.nih.gov/pubmed/28545963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijbiomac.2017.05.119
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