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Insulin Stimulation of GLUT4 Exocytosis, but Not Its Inhibition of Endocytosis, Is Dependent on RabGAP AS160

Insulin maintains whole body blood glucose homeostasis, in part, by regulating the amount of the GLUT4 glucose transporter on the cell surface of fat and muscle cells. Insulin induces the redistribution of GLUT4 from intracellular compartments to the plasma membrane, by stimulating a large increase...

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Detalhes bibliográficos
Main Authors: Zeigerer, Anja, McBrayer, Mary Kate, McGraw, Timothy E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC519136/
https://ncbi.nlm.nih.gov/pubmed/15254270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0333
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