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Insulin Stimulation of GLUT4 Exocytosis, but Not Its Inhibition of Endocytosis, Is Dependent on RabGAP AS160

Insulin maintains whole body blood glucose homeostasis, in part, by regulating the amount of the GLUT4 glucose transporter on the cell surface of fat and muscle cells. Insulin induces the redistribution of GLUT4 from intracellular compartments to the plasma membrane, by stimulating a large increase...

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Autori principali: Zeigerer, Anja, McBrayer, Mary Kate, McGraw, Timothy E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC519136/
https://ncbi.nlm.nih.gov/pubmed/15254270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-04-0333
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