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Insulin Stimulation of GLUT4 Exocytosis, but Not Its Inhibition of Endocytosis, Is Dependent on RabGAP AS160

Insulin maintains whole body blood glucose homeostasis, in part, by regulating the amount of the GLUT4 glucose transporter on the cell surface of fat and muscle cells. Insulin induces the redistribution of GLUT4 from intracellular compartments to the plasma membrane, by stimulating a large increase...

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Publicado en:Mol Biol Cell
Autores principales: Zeigerer, Anja, McBrayer, Mary Kate, McGraw, Timothy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Cell Biology 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC519136/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15254270/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.E04-04-0333
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