The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy

Autophagy is an evolutionarily conserved process that enables catabolic and degradative pathways. These pathways commonly depend on vesicular transport controlled by Rabs, small GTPases inactivated by TBC/RabGAPs. The Rac1 effector TBC/RabGAP Armus (TBC1D2A) is known to inhibit Rab7, a key regulator...

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Hlavní autoři: Carroll, Bernadette, Mohd-Naim, Noor, Maximiano, Filipe, Frasa, Marieke A., McCormack, Jessica, Finelli, Mattea, Thoresen, Sigrid B., Perdios, Louis, Daigaku, Reiko, Francis, Richard E., Futter, Clare, Dikic, Ivan, Braga, Vania M.M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898768/
https://ncbi.nlm.nih.gov/pubmed/23562278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.005
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