The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy

Autophagy is an evolutionarily conserved process that enables catabolic and degradative pathways. These pathways commonly depend on vesicular transport controlled by Rabs, small GTPases inactivated by TBC/RabGAPs. The Rac1 effector TBC/RabGAP Armus (TBC1D2A) is known to inhibit Rab7, a key regulator...

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Detalhes bibliográficos
Main Authors: Carroll, Bernadette, Mohd-Naim, Noor, Maximiano, Filipe, Frasa, Marieke A., McCormack, Jessica, Finelli, Mattea, Thoresen, Sigrid B., Perdios, Louis, Daigaku, Reiko, Francis, Richard E., Futter, Clare, Dikic, Ivan, Braga, Vania M.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3898768/
https://ncbi.nlm.nih.gov/pubmed/23562278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.03.005
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