The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans

Once loaded onto Argonaute proteins, microRNAs form a silencing complex called miRISC that targets mostly the 3’UTR of mRNAs to silence their translation. How microRNAs are transported to and from their target mRNA remains poorly characterized. While some reports linked intracellular trafficking to...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Michaud, Pascale, Shah, Vivek Nilesh, Adjibade, Pauline, Houle, Francois, Quévillon Huberdeau, Miguel, Rioux, Rachel, Lavoie-Ouellet, Camille, Gu, Weifeng, Mazroui, Rachid, Simard, Martin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055011/
https://ncbi.nlm.nih.gov/pubmed/33826611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009511
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