The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans

Once loaded onto Argonaute proteins, microRNAs form a silencing complex called miRISC that targets mostly the 3’UTR of mRNAs to silence their translation. How microRNAs are transported to and from their target mRNA remains poorly characterized. While some reports linked intracellular trafficking to...

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Vydáno v:PLoS Genet
Hlavní autoři: Michaud, Pascale, Shah, Vivek Nilesh, Adjibade, Pauline, Houle, Francois, Quévillon Huberdeau, Miguel, Rioux, Rachel, Lavoie-Ouellet, Camille, Gu, Weifeng, Mazroui, Rachid, Simard, Martin J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2021
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055011/
https://ncbi.nlm.nih.gov/pubmed/33826611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009511
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