The RabGAP TBC-11 controls Argonaute localization for proper microRNA function in C. elegans

Once loaded onto Argonaute proteins, microRNAs form a silencing complex called miRISC that targets mostly the 3’UTR of mRNAs to silence their translation. How microRNAs are transported to and from their target mRNA remains poorly characterized. While some reports linked intracellular trafficking to...

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Dettagli Bibliografici
Pubblicato in:PLoS Genet
Autori principali: Michaud, Pascale, Shah, Vivek Nilesh, Adjibade, Pauline, Houle, Francois, Quévillon Huberdeau, Miguel, Rioux, Rachel, Lavoie-Ouellet, Camille, Gu, Weifeng, Mazroui, Rachid, Simard, Martin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2021
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8055011/
https://ncbi.nlm.nih.gov/pubmed/33826611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009511
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